Manfred Lopez Grem is the founder of a small non-profit organization in Mexico focused on independent filmmaking. His work has included founding non-profit online talent platforms for writers, actors, dancers and other artists. As a film director he has directed around 30 short films, as well as documentaries, commercials, tv programs and other types of works. He also maintains an active schedule teaching workshops, offering consulting services, keynoting conferences, and heading casting tours in several cities as part of his work related to Mexico's National Actor's Registry.

His professional activities have been covered extensively in Mexico's media. Over 150 articles have been published on the topic to date, including magazine and newspaper coverage from Variety, Proceso and El Universal.